Lafaxine^®ER

Therapeutic Segment:
Anti-depressant

Generic Name:
Desvenlafaxine

Description:
Desvenlafaxine is an extended-release tablet for oral administration that contains desvenlafaxine succinate, a Desvenlafaxine is designated RS-4-[2-dimethylamino-1 -(1 -hydroxycyclohexyl) ethyl] phenol and has the empirical formula of C16H25NO2C4H6O4.H2O (Desvenlafaxine succinate monohydrate).

Indication:
Desvenlafaxine a selective serotonin and norepinephrine re-uptake inhibitor (SNRI) is indicated for the treatment of major depressive disorder (MDD). A major depressive episode (DSM-IV) implies a prominent and relatively persistent (nearly every day for at least 2 weeks) depressed or dysphoric mood that usually interferes with daily functioning, and includes at least 5 of the following 9 symptoms: depressed mood, loss of interest in usual activities, significant change in weight and/or appetite, insomnia or hypersomnia, psychomotor agitation or retardation, increased fatigue, feelings of guilt or worthlessness, slowed thinking or impaired concentration, or a suicide attempt or suicidal ideation.

Formulation: